Bismuth powder is widely used in the pharmaceutical industry, particularly in the formulation of gastrointestinal medications. It acts as an active ingredient in treatments for ulcers, gastritis, and diarrhea due to its antimicrobial and protective properties on the stomach lining.

In metallurgy, bismuth powder serves as an additive in lead-free alloys, especially in solders and fusible alloys, where it contributes to low melting points and improved machinability. Its low toxicity compared to other heavy metals makes it suitable for applications in plumbing fixtures and fittings intended for drinking water systems.

The powder is also employed in the production of electronic materials, including semiconductors and thermoelectric devices, where it functions as a precursor or dopant. Additionally, bismuth powder finds use in catalysts for synthetic chemistry, enhancing reaction efficiency in processes like selective oxidation.

In cosmetics, it is processed into bismuth oxychloride for use in pigments that provide a pearlescent effect in makeup products such as eye shadows, nail polishes, and face powders.

Due to its high density and low neutron emission, bismuth powder is increasingly used as a safer alternative to lead in ammunition and radiation shielding, particularly in medical and industrial protective equipment.