Widely used in asymmetric catalysis, this compound serves as a chiral ligand in various enantioselective transformations. It is particularly effective in copper-catalyzed cyclopropanation and conjugate addition reactions, where it helps achieve high enantiomeric excess. Due to its rigid C2-symmetric structure, it promotes well-defined transition states, enhancing stereocontrol. It is also employed in nickel- and palladium-catalyzed reactions for the synthesis of optically active compounds, making it valuable in pharmaceutical and fine chemical industries for producing single-enantiomer products.