Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation, cyclopropanation, and Diels-Alder reactions. Its rigid pyridine backbone and oxazoline rings provide excellent stereocontrol when coordinated to transition metals like copper, nickel, or iridium. It is particularly effective in promoting high enantioselectivity in C–C bond-forming reactions and in the synthesis of optically active pharmaceutical intermediates. Due to its modular synthesis and tunable steric environment, it is favored in both academic research and industrial processes for producing single-enantiomer compounds.