2,2-Bis((4R,5S)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)acetonitrile
97%
Reagent
Code: #152338
CAS Number
1222193-12-5
blur_circular Chemical Specifications
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Molecular Information
Weight
483.56 g/mol
Formula
C₃₂H₂₅N₃O₂
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, particularly in enantioselective hydrogenation and transfer hydrogenation reactions. Its rigid, C2-symmetric structure enhances stereocontrol, making it effective in producing high enantiomeric excess in the synthesis of chiral amines, alcohols, and other pharmaceutical intermediates. Commonly employed with transition metals such as ruthenium, rhodium, and iridium to form catalysts for the production of fine chemicals and active pharmaceutical ingredients. Due to its strong coordination and steric properties, it supports efficient catalytic turnover and excellent selectivity in industrial and academic research settings.
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