2, 6-Bis((S)-4-isopropyl-5, 5-diphenyl-4, 5-dihydrooxazol-2-yl)pyridine
98%, 99%e.e.
Reagent
Code: #151932
CAS Number
162213-03-8
blur_circular Chemical Specifications
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Molecular Information
Weight
605.77 g/mol
Formula
C₄₁H₃₉N₃O₂
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Registry Numbers
MDL Number
MFCD18379147
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations. It forms effective complexes with transition metals like rhodium, ruthenium, and iridium, which are employed in hydrogenation reactions of prochiral substrates such as ketones, alkenes, and imines. Due to its rigid pyridine backbone and bulky chiral oxazoline arms, it imparts high stereoselectivity, leading to high enantiomeric excess in the products. It is particularly valuable in the synthesis of pharmaceutical intermediates and fine chemicals where precise stereochemistry is required. Its stability under various reaction conditions makes it suitable for both academic research and industrial applications in asymmetric synthesis.
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