1,3-Bis((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)benzene
98%
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations. It forms complexes with transition metals such as rhodium, ruthenium, and iridium, which are employed in hydrogenation reactions of prochiral substrates like ketones, alkenes, and imines. These reactions are essential in the synthesis of optically active pharmaceuticals and fine chemicals. Due to its rigid aromatic backbone and well-defined chiral environment, it provides high enantioselectivity and catalytic efficiency in various synthetic routes. Its application is particularly valuable in the development of single-enantiomer drugs where stereochemical purity is critical.
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