Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations. It forms complexes with transition metals such as rhodium, ruthenium, and iridium, which are highly effective in hydrogenation reactions of prochiral substrates like ketones, alkenes, and imines. These catalytic systems deliver high enantiomeric excess (ee), making them valuable in the synthesis of chiral pharmaceuticals and fine chemicals. Its rigid pyridine backbone and well-defined chiral pockets enhance stereocontrol, offering reproducible results in industrial and academic research settings. The ligand is particularly favored in reactions where precise spatial arrangement of the metal center is critical for selectivity.