This chiral bis(oxazoline) ligand, featuring a rigid indeno-fused structure connected by a methylene bridge, is primarily utilized in asymmetric catalysis. It coordinates with transition metals such as copper, palladium, or ruthenium to enable highly enantioselective reactions, including Diels-Alder cycloadditions, aldol reactions, allylic substitutions, and conjugate additions. This makes it essential for the synthesis of enantiomerically pure intermediates in the pharmaceutical industry, particularly for producing chiral active pharmaceutical ingredients (APIs) and complex natural products. Its specificity and efficiency in stereocontrol also extend to applications in fine chemical manufacturing and materials science where optical purity is required.