17α-Hydroxyprogesterone is a synthetic steroid hormone and a key intermediate in the biosynthesis and chemical synthesis of various steroid hormones, including progesterone derivatives, corticosteroids, and glucocorticoids. It is widely used in pharmaceutical research and manufacturing for developing treatments for endocrine disorders, such as adrenal insufficiency and congenital adrenal hyperplasia, where it aids in hormone regulation pathways. In obstetrics, its esters (e.g., 17α-hydroxyprogesterone caproate) are employed to prevent preterm labor in high-risk pregnancies by promoting uterine quiescence. This high-purity compound is also valuable in biochemical studies and as a reference standard in analytical chemistry.