Widely used in hormone replacement therapy (HRT) to manage symptoms of menopause such as hot flashes, vaginal dryness, and mood changes. Helps regulate the menstrual cycle and is used to treat irregular periods and absence of menstruation (amenorrhea). Employed in fertility treatments to support the luteal phase and maintain early pregnancy, especially in assisted reproductive technologies like IVF. Used to prevent endometrial hyperplasia in women taking estrogen after menopause. Applied in the treatment of certain menstrual disorders, including severe premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD). Available in various forms such as oral tablets, vaginal gels, suppositories, and injections, allowing flexible dosing based on clinical need. Also used in some contraceptive formulations to regulate ovulation and support endometrial changes.