This Fmoc-protected propargylamine is a key building block in organic synthesis, especially peptide chemistry and bioconjugation. The fluorenylmethoxycarbonyl (Fmoc) group facilitates incorporation into solid-phase peptide synthesis due to its stability under basic conditions and straightforward removal using mild bases like piperidine. The prop-2-yn-1-yl (propargyl) moiety enables post-synthetic modification via click chemistry (CuAAC), allowing attachment of diverse molecular entities. This orthogonal dual functionality is essential for pharmaceuticals, bioconjugates, materials science, complex biomolecule assembly, and advanced drug delivery systems.