Used as a highly efficient coupling reagent in peptide synthesis, enabling rapid amide bond formation under mild conditions. Its unique structure enhances reactivity and reduces racemization, making it valuable in solid-phase peptide synthesis and the preparation of complex peptides for pharmaceutical research. Also applied in bioconjugation processes, where selective and clean reactions are required, such as labeling biomolecules with fluorescent tags or attaching payloads in antibody-drug conjugates. Shows good solubility in polar aprotic solvents, facilitating its use in automated synthesis platforms.