2-Ethyl-3-methylmaleimide N-β-D-glucopyranoside
97%
science Other reagents with same CAS 182228-46-2
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Used as a glycosylation reagent in medicinal chemistry to improve the solubility and bioavailability of drug candidates. It serves as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents by combining the targeting ability of antibodies with the potency of small molecule drugs. Its maleimide group allows for selective conjugation with thiol groups via Michael addition, while the glucopyranoside moiety enhances water solubility and reduces immunogenicity. Also employed in the development of glycoconjugate vaccines and in biochemical research for labeling and detecting biomolecules.
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