3-[(3-Acrylamidopropyl)dimethylammonio]propane-1-sulfonate is a zwitterionic surfactant and polymerizable monomer. As a surfactant, it is used in electrophoresis, particularly SDS-PAGE, to improve protein solubility, reduce non-specific binding, and enhance resolution of membrane proteins and hydrophobic peptides by maintaining stability in denaturing conditions. It is commonly applied in proteomics research for sample preparation, solubilizing proteins without interfering with mass spectrometry, and in buffer formulations to minimize aggregation and preserve native-like conformations. Additionally, its acrylamide group enables use as a co-monomer in synthesizing water-soluble, biocompatible polymers, such as hydrogels for controlled drug delivery, medical products, cosmetics, and anti-fouling coatings that resist protein and microbial adhesion.