Histidylphenylalanine is primarily utilized in the field of biochemistry and medical research due to its role as a dipeptide. It is often studied for its potential effects on neurological functions and its involvement in peptide synthesis. Researchers explore its application in understanding metabolic pathways and its possible therapeutic benefits in treating conditions related to peptide imbalances. Additionally, it serves as a model compound in studies focusing on peptide bond formation and degradation, providing insights into enzymatic processes and protein engineering. Its relevance in nutritional science is also noted, particularly in examining the bioavailability and physiological impact of dipeptides in dietary supplements.