VIP(6-28) is a fragment of the vasoactive intestinal peptide (VIP) and is primarily used in research to study the role of VIP in various physiological processes. It acts as a VIP receptor antagonist, making it valuable for investigating the mechanisms of VIP in the body.

In neuroscience, VIP(6-28) is utilized to explore VIP's effects on circadian rhythms, neurotransmission, and neuroprotection. It helps researchers understand how VIP influences brain function and behavior.

In immunology, this peptide is used to study VIP's role in modulating immune responses, particularly its anti-inflammatory effects and its impact on immune cell activity.

Additionally, VIP(6-28) is employed in cardiovascular research to examine VIP's role in regulating blood pressure, heart rate, and vascular tone. By blocking VIP receptors, researchers can better understand its contribution to cardiovascular health and disease.

Overall, VIP(6-28) serves as a critical tool in biomedical research, aiding in the exploration of VIP's diverse functions in the nervous, immune, and cardiovascular systems.