Apelin-13 is widely studied for its role in cardiovascular regulation. It acts as a potent vasodilator, helping to lower blood pressure by relaxing blood vessels. This peptide is also being explored for its potential in treating heart failure, as it improves cardiac output and reduces the workload on the heart. Additionally, Apelin-13 shows promise in metabolic regulation, particularly in glucose metabolism and insulin sensitivity, making it a candidate for diabetes research. Its neuroprotective effects are also under investigation, with potential applications in treating neurodegenerative diseases. Furthermore, it has been studied for its role in angiogenesis, which could be beneficial in wound healing and tissue repair.