Dynorphin A (1-17) is primarily involved in modulating pain and stress responses within the central nervous system. It acts as an endogenous opioid peptide, binding to kappa-opioid receptors to produce analgesic effects, though it can also contribute to dysphoria under certain conditions. This peptide plays a role in regulating mood, memory, and addiction pathways, making it a subject of interest in neuropsychiatric research. It is also studied for its potential in understanding and treating chronic pain, depression, and substance abuse disorders. Additionally, Dynorphin A (1-17) is used in experimental models to explore its influence on neuroinflammation and neurodegenerative diseases.