Substance P xTFA is widely utilized in neuroscience and pharmacological research due to its role as a neuropeptide involved in pain signaling and inflammation. It is commonly used in experimental studies to investigate the mechanisms of nociception, as it binds to and activates the neurokinin-1 (NK1) receptor. Researchers apply it in vitro and in vivo models to study its effects on pain pathways, neurogenic inflammation, and its potential therapeutic applications in conditions like chronic pain, migraines, and inflammatory diseases. Additionally, it serves as a valuable tool in understanding the pathophysiology of disorders related to the central and peripheral nervous systems.