Tuftsin trifluoroacetate is primarily used in immunological research due to its ability to enhance phagocytic activity of immune cells such as neutrophils and macrophages. It acts as an immunostimulant by promoting the migration and engulfment of pathogens by these cells, making it valuable in studies focused on host defense mechanisms. Researchers also explore its potential in vaccine adjuvants to boost immune response. Additionally, it has been investigated for use in cancer immunotherapy, where enhancing the body’s natural phagocytic activity may support tumor cell clearance. Its stability in trifluoroacetate form makes it suitable for in vitro and in vivo experimental models.