Used in neuroscience research to study myelin basic protein (MBP) interactions and immune responses related to demyelinating diseases such as multiple sclerosis. The Ala113 substitution enhances stability and supports epitope mapping in T-cell activation studies. Commonly employed in experimental autoimmune encephalomyelitis (EAE) models to induce immune-mediated demyelination. The TFA salt form improves solubility for in vitro and in vivo applications.