This peptide is primarily utilized in research focused on understanding the mechanisms of HIV-1 infection and replication. It plays a critical role in studying the function of the Rev protein, which is essential for the transport of viral RNA from the nucleus to the cytoplasm in infected cells. Researchers use this peptide to investigate how Rev interacts with other viral and host cell components, aiming to develop potential antiviral therapies. Additionally, it serves as a valuable tool in assays designed to screen for compounds that can inhibit Rev activity, thereby disrupting the viral life cycle. Its application extends to the study of nuclear export pathways and the development of targeted treatments for HIV-1.