GRGDSPK is widely used in biomedical research, particularly in studies focusing on cell adhesion and tissue engineering. Its primary application is as a synthetic peptide that mimics the natural binding sites of extracellular matrix proteins, such as fibronectin. This allows researchers to study how cells interact with their environment, promoting or inhibiting cell attachment, spreading, and migration. It is also utilized in the development of biomaterials, where it is incorporated into scaffolds to enhance cell integration and tissue regeneration. Additionally, GRGDSPK plays a role in cancer research, as it can be used to investigate tumor cell behavior and metastasis. Its ability to modulate cell adhesion makes it a valuable tool in drug discovery and therapeutic applications aimed at targeting specific cellular processes.