17(R)-Resolvin D4 is primarily recognized for its role in resolving inflammation and promoting tissue repair. It is a specialized pro-resolving mediator (SPM) derived from omega-3 fatty acids, which actively contributes to the termination of inflammatory responses and the restoration of homeostasis. This compound is particularly effective in modulating immune cell functions, such as reducing neutrophil infiltration and enhancing macrophage activity to clear cellular debris. Its application is significant in managing chronic inflammatory conditions, including cardiovascular diseases, arthritis, and neurodegenerative disorders. Additionally, it has shown potential in supporting recovery after injury or surgery by accelerating the healing process and minimizing excessive inflammation. Research continues to explore its therapeutic benefits in various inflammatory and autoimmune diseases.