15-deoxy-Δ12,14-PGJ2 is widely used in biomedical research due to its role as a potent signaling molecule. It is primarily studied for its anti-inflammatory and pro-apoptotic properties, making it valuable in understanding cellular responses to stress and inflammation. Researchers utilize it to investigate pathways involving nuclear receptors, particularly PPARγ, which plays a critical role in metabolism and immune regulation. It is also employed in studies focused on oxidative stress and neurodegenerative diseases, as it can modulate cellular redox states. Additionally, this compound is used in cancer research to explore its effects on tumor cell proliferation and apoptosis. Its applications extend to studying metabolic disorders, where it helps elucidate mechanisms related to insulin sensitivity and lipid metabolism.