15-deoxy-Δ12,14-PGD2 is primarily studied for its role in inflammatory and immune responses. It acts as a potent anti-inflammatory agent by inhibiting the activation of nuclear factor-kappa B (NF-κB), a key regulator of inflammation. This makes it a potential therapeutic candidate for conditions like arthritis, asthma, and other inflammatory diseases. Additionally, it has been investigated for its role in regulating cell proliferation and apoptosis, suggesting potential applications in cancer research. Its ability to modulate immune cell function also highlights its relevance in autoimmune disorders and immune system regulation.