15-OxoETE (15-KETE) is primarily studied for its role in inflammatory processes and cellular signaling pathways. It is involved in the regulation of immune responses and has been linked to the modulation of inflammation in various diseases. Research suggests that it may act as a signaling molecule in the resolution of inflammation, potentially influencing the activity of immune cells such as neutrophils and macrophages. Additionally, it has been investigated for its role in vascular biology, where it may contribute to the regulation of blood vessel function and integrity. Its involvement in lipid metabolism and oxidative stress pathways also makes it a subject of interest in studies related to metabolic disorders and chronic inflammatory conditions.