1,1'-Bis(dicyclohexylphosphino)ferrocene is widely used as a ligand in transition metal catalysis, particularly in asymmetric synthesis and cross-coupling reactions. Its unique ferrocene backbone and bulky dicyclohexylphosphine groups make it highly effective in stabilizing metal complexes and enhancing catalytic activity. It is commonly employed in palladium-catalyzed reactions, such as Suzuki-Miyaura and Heck couplings, where it improves selectivity and yield. Additionally, its chiral derivatives are valuable in enantioselective transformations, including hydrogenation and carbon-carbon bond formation, making it a key component in the synthesis of pharmaceuticals and fine chemicals. The ligand’s robustness and versatility also make it suitable for use in challenging reaction conditions.