Used as a key intermediate in the synthesis of strained bicyclic compounds for drug discovery, particularly in the development of bioisosteres that mimic phenyl or tert-butyl groups. Its unique three-dimensional structure enhances metabolic stability and improves pharmacokinetic properties in pharmaceuticals. Commonly employed in fragment-based drug design and covalent inhibitor development due to the reactivity of the bromine atom, which allows further functionalization via cross-coupling reactions. Also utilized in materials science to introduce rigidity into molecular architectures.