Used in pharmaceutical research as a rigid bioisostere for phenyl or other aromatic groups, enhancing metabolic stability and solubility in drug candidates. Its unique bridged bicyclo[1.1.1]pentane structure improves binding selectivity and pharmacokinetic properties, making it valuable in designing CNS drugs, enzyme inhibitors, and compounds requiring reduced off-target effects. Also explored in agrochemicals for developing novel active ingredients with improved environmental profiles.