(Z)-2-(2-Aminothiazole-4-yl-)-2-trityloxyimino acetic acid
98%
Reagent
Code: #38661
CAS Number
128438-01-7
blur_circular Chemical Specifications
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Molecular Information
Weight
429.49 g/mol
Formula
C₂₄H₁₉N₃O₃S
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Registry Numbers
MDL Number
MFCD08458707
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Physical Properties
Melting Point
179-182 °C (lit.)
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Storage & Handling
Storage
room temperature
description Product Description
This compound is primarily utilized in the synthesis of cephalosporin antibiotics, serving as a key intermediate for introducing the 2-(2-aminothiazol-4-yl)-2-(trityloxyimino)acetyl side chain via acylation onto the cephalosporin nucleus (e.g., 7-ACA derivatives). The trityl group serves as a protecting group for the oxime hydroxyl, enabling selective reactivity during synthesis. The compound is also employed in research and development for creating new antibiotic derivatives, aiding in the fight against resistant bacterial strains. Additionally, it finds use in pharmaceutical manufacturing processes where precise chemical intermediates are required for large-scale drug production.
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