4-(2-Amino-4-thiazolyl)benzoic Acid
≥97%
Reagent
Code: #172683
CAS Number
216959-94-3
blur_circular Chemical Specifications
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Molecular Information
Weight
220.25 g/mol
Formula
C₁₀H₈N₂O₂S
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Registry Numbers
MDL Number
MFCD01460736
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of cephalosporin antibiotics, particularly in the production of third-generation cephalosporins like ceftazidime and ceftriaxone. Its structure enables beta-lactam ring integration, enhancing antibacterial activity against a broad spectrum of Gram-negative and some Gram-positive bacteria. Commonly employed in pharmaceutical research and development for creating semi-synthetic antibiotics with improved stability and resistance to beta-lactamases. Also utilized in the preparation of derivatives for structure-activity relationship studies in antimicrobial drug design.
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