(±)-Befunolol is primarily used as a beta-blocker in the treatment of glaucoma and ocular hypertension. It works by reducing the production of aqueous humor in the eye, thereby lowering intraocular pressure. This helps in preventing damage to the optic nerve and preserving vision. Additionally, it may be used in other conditions where beta-adrenergic blockade is beneficial, such as managing certain cardiovascular disorders. Its application is often in the form of ophthalmic solutions for direct administration to the eye, ensuring localized effect with minimal systemic absorption.