4-(Bromomethyl)-2-fluoro-1-(trifluoromethyl)benzene
98%
Reagent
Code: #152494
CAS Number
213203-65-7
blur_circular Chemical Specifications
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Molecular Information
Weight
257.02 g/mol
Formula
C₈H₅BrF₄
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Registry Numbers
MDL Number
MFCD00236289
thermostat
Physical Properties
Melting Point
25-27 °C
Boiling Point
206.8 °C at 760 mmHg
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Storage & Handling
Density
1.640±0.06 g/cm3(Predicted)
Storage
Room temperature, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the bromomethyl group enables further functionalization through cross-coupling reactions. Its electron-withdrawing trifluoromethyl and fluoro substituents enhance metabolic stability in drug candidates. Commonly employed in the preparation of kinase inhibitors and anti-inflammatory agents. Also utilized in agrochemical synthesis for building complex aromatic structures with improved bioavailability and target selectivity.
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