tert-Butyl 4-(bromomethyl)benzylcarbamate
97%
Reagent
Code: #146195
CAS Number
187283-17-6
science Other reagents with same CAS 187283-17-6
blur_circular Chemical Specifications
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Molecular Information
Weight
300.19 g/mol
Formula
C₁₃H₁₈BrNO₂
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and bioactive molecules. The compound’s bromomethyl group allows for nucleophilic substitution reactions, enabling the introduction of various functional groups. It is commonly employed in the construction of peptidomimetics and targeted protein degraders, such as PROTACs, due to the presence of a handle for linker attachment. The tert-butyl carbamate (Boc) group provides amine protection during multi-step syntheses, ensuring selective reactivity. Its stability under a range of conditions and clean deprotection profile make it valuable in medicinal chemistry workflows.
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