6-Bromo-1,4-dihydro-2H-3,1-benzoxazin-2-one
97%
Reagent
Code: #150271
CAS Number
1017783-09-3
blur_circular Chemical Specifications
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Molecular Information
Weight
228.04 g/mol
Formula
C₈H₆BrNO₂
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Registry Numbers
MDL Number
MFCD09972273
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Physical Properties
Melting Point
187-188 °C
Boiling Point
260.1 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of benzoxazine derivatives, which serve as important precursors for bioactive pharmaceutical compounds, particularly in the areas of antimicrobials, antivirals, and central nervous system therapeutics. The bromine substituent enables facile subsequent reactions, such as nucleophilic substitution or carbon-carbon bond formation through copper- or palladium-catalyzed couplings, making it suitable for structural modifications during the development of new drugs. Its reactivity also supports the preparation of fused heterocyclic systems for broader medicinal chemistry applications.
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