DAABD-Cl is widely used in proteome analysis for the selective labeling and detection of thiol-containing compounds, such as cysteine residues in proteins. Its application is particularly valuable in fluorescence-based assays, where it reacts with thiol groups to form highly fluorescent derivatives, enabling sensitive and specific detection. This reagent is employed in the study of protein structure, function, and interactions, as well as in the identification and quantification of thiols in complex biological samples. Additionally, DAABD-Cl is utilized in the analysis of redox states and oxidative stress in cells, providing insights into cellular mechanisms and disease pathways. Its high selectivity and sensitivity make it a crucial tool in biochemical and proteomic research.