6-(1-Hydroxy-1,3-dihydro-benzo[c][1,2]oxaborol-5-yloxy)-2-(2-methoxy-ethoxy)-nicotinonitrile
≥95%
Reagent
Code: #196171
CAS Number
1187187-28-5
blur_circular Chemical Specifications
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Molecular Information
Weight
326.11 g/mol
Formula
C₁₆H₁₅BN₂O₅
thermostat
Physical Properties
Boiling Point
508.0±60.0 °C(Predicted)
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Storage & Handling
Density
1.34±0.1 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting BTK (Bruton's tyrosine kinase) for the treatment of autoimmune diseases and certain cancers. Its boron-containing structure enhances binding selectivity and potency in drug candidates. Also explored in prodrug formulations due to improved solubility and metabolic stability. Commonly applied in structure-activity relationship (SAR) studies to optimize pharmacokinetic properties in oncology and inflammation pipelines.
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