1-Hydroxy-6-(trifluoromethyl)benzo[c][1,2]oxaborol-3(1H)-one
97%
Reagent
Code: #192856
CAS Number
2828438-87-3
blur_circular Chemical Specifications
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Molecular Information
Weight
215.92 g/mol
Formula
C₈H₄BF₃O₃
thermostat
Physical Properties
Boiling Point
289.7±50.0 °C(Predicted)
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Storage & Handling
Density
1.51±0.1 g/cm3(Predicted)
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of boron-containing pharmaceuticals, particularly in the development of proteasome inhibitors for cancer therapy. Its unique boron heterocycle structure enhances binding affinity to target enzymes, improving drug efficacy. Also employed in agrochemicals for creating novel fungicides due to its metabolic stability and bioavailability. The trifluoromethyl group contributes to increased lipophilicity and membrane permeability, making it valuable in optimizing pharmacokinetic properties of active compounds.
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