3-Fluoro-4-iodobenzonitrile

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Reagent Code: #81071
label
Alias 4-cyano-2-fluoroiodobenzene
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CAS Number 887266-99-1

science Other reagents with same CAS 887266-99-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 247.01 g/mol
Formula C₇H₃FIN
badge Registry Numbers
MDL Number MFCD07782076
thermostat Physical Properties
Melting Point 110-113°C
Boiling Point 268℃
inventory_2 Storage & Handling
Density 1.98
Storage room temperature

description Product Description

3-Fluoro-4-iodobenzonitrile is primarily used in organic synthesis as a versatile building block for the development of more complex chemical structures. Its unique combination of fluorine and iodine substituents on the aromatic ring makes it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. The fluorine atom often enhances the biological activity and metabolic stability of the final compounds, while the iodine atom allows for further functionalization through cross-coupling reactions, such as Suzuki or Sonogashira couplings. This chemical is particularly useful in the preparation of active pharmaceutical ingredients (APIs) and in the discovery of new drug candidates, where its structural features can be leveraged to optimize drug properties. Additionally, it serves as a key intermediate in the synthesis of advanced materials and specialty chemicals, where its halogenated aromatic core can be tailored for specific applications.

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Test Parameter Specification
Melting Point 113-117
Purity (HPLC) 97-100%
Combustion 96.5-103.5%
Appearance White to orange to tan solid
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿350.00
inventory 5g
10-20 days ฿730.00
inventory 25g
10-20 days ฿3,310.00
inventory 100g
10-20 days ฿12,610.00
inventory 250mg
10-20 days ฿250.00

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3-Fluoro-4-iodobenzonitrile
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3-Fluoro-4-iodobenzonitrile is primarily used in organic synthesis as a versatile building block for the development of more complex chemical structures. Its unique combination of fluorine and iodine substituents on the aromatic ring makes it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. The fluorine atom often enhances the biological activity and metabolic stability of the final compounds, while the iodine atom allows for further functionalization through cross-coupling reactions, such as Suzuki or Sonogashira couplings. This chemical is particularly useful in the preparation of active pharmaceutical ingredients (APIs) and in the discovery of new drug candidates, where its structural features can be leveraged to optimize drug properties. Additionally, it serves as a key intermediate in the synthesis of advanced materials and specialty chemicals, where its halogenated aromatic core can be tailored for specific applications.
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