3-Fluoro-4-iodobenzonitrile
97%
Reagent
Code: #81071
Alias
4-cyano-2-fluoroiodobenzene
CAS Number
887266-99-1
science Other reagents with same CAS 887266-99-1
blur_circular Chemical Specifications
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Molecular Information
Weight
247.01 g/mol
Formula
C₇H₃FIN
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Registry Numbers
MDL Number
MFCD07782076
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Physical Properties
Melting Point
110-113°C
Boiling Point
268℃
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Storage & Handling
Density
1.98
Storage
room temperature
description Product Description
3-Fluoro-4-iodobenzonitrile is primarily used in organic synthesis as a versatile building block for the development of more complex chemical structures. Its unique combination of fluorine and iodine substituents on the aromatic ring makes it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. The fluorine atom often enhances the biological activity and metabolic stability of the final compounds, while the iodine atom allows for further functionalization through cross-coupling reactions, such as Suzuki or Sonogashira couplings. This chemical is particularly useful in the preparation of active pharmaceutical ingredients (APIs) and in the discovery of new drug candidates, where its structural features can be leveraged to optimize drug properties. Additionally, it serves as a key intermediate in the synthesis of advanced materials and specialty chemicals, where its halogenated aromatic core can be tailored for specific applications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 113-117 |
| Purity (HPLC) | 97-100% |
| Combustion | 96.5-103.5% |
| Appearance | White to orange to tan solid |
| Infrared Spectrum | Conforms to Structure |
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