4-Iodo-2-(trifluoromethyl)benzamide
97%
Reagent
Code: #200303
CAS Number
1195677-97-4
blur_circular Chemical Specifications
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Molecular Information
Weight
315.03 g/mol
Formula
C₈H₅F₃INO
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Storage & Handling
Storage
2-8°C, dry and sealed from light
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and other bioactive molecules. Its structure allows for selective cross-coupling reactions, making it valuable in medicinal chemistry for constructing complex aromatic systems. Commonly employed in Suzuki and Buchwald–Hartwig reactions to introduce aryl or amino groups. Also utilized in the preparation of fluorinated analogs in drug discovery, where the trifluoromethyl group enhances metabolic stability and lipophilicity.
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