2-Fluoro-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
95%
Reagent
Code: #188839
CAS Number
1374508-59-4
blur_circular Chemical Specifications
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Molecular Information
Weight
265.09 g/mol
Formula
C₁₃H₁₇BFNO₃
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Registry Numbers
MDL Number
MFCD18730402
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Physical Properties
Boiling Point
349.7±37.0 °C(Predicted)
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Storage & Handling
Density
1.17±0.1 g/cm3(Predicted)
Storage
Room temperature, inert gas
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds in pharmaceutical and agrochemical research. Its boronate ester group enables efficient carbon-carbon bond formation under mild conditions. The fluorine substituent enhances reactivity and influences the electronic properties of the final product, making it valuable in the development of functionalized aromatic amides for drug discovery. Commonly employed in late-stage functionalization due to good stability and selectivity in coupling processes.
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