4-Bromo-3-fluoro-N-methoxy-N-methyl-benzamide
98%
science Other reagents with same CAS 343564-56-7
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical and agrochemical compounds, this Weinreb amide (N-methoxy-N-methylbenzamide derivative) facilitates the selective formation of ketones via reaction with organometallic reagents due to its chelating properties. The 4-bromo-3-fluoro substitution on the aromatic ring enables directed cross-coupling reactions, such as Suzuki-Miyaura or Buchwald-Hartwig couplings, for constructing complex fluorinated and brominated aromatic scaffolds. It is particularly valuable in medicinal chemistry for drug discovery, enhancing metabolic stability and binding affinity in active pharmaceutical ingredients, and in agrochemical research for bioactive molecules with improved environmental stability.
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