HA-14-1 is primarily utilized in biochemical research as a small molecule inhibitor targeting the Bcl-2 family of proteins, which play a critical role in regulating apoptosis (programmed cell death). It is particularly used in studies focused on understanding the mechanisms of cell survival and death, especially in cancer research. By inhibiting Bcl-2, HA-14-1 promotes apoptosis in cancer cells, making it a valuable tool for investigating potential therapeutic strategies for cancer treatment. Additionally, it aids in exploring the role of Bcl-2 in various diseases where apoptosis is dysregulated, such as neurodegenerative disorders and autoimmune conditions. Its application is largely confined to laboratory settings for experimental purposes.