PBS-EDTA solution is widely used in biological and biochemical research for cell dissociation and tissue preparation. It helps in breaking down cell-to-cell and cell-to-matrix interactions, making it essential for isolating cells from tissues. The solution is also employed in molecular biology techniques, such as DNA and RNA extraction, where it aids in chelating divalent cations to prevent enzymatic degradation of nucleic acids. Additionally, PBS-EDTA is used in immunohistochemistry and flow cytometry to wash and preserve samples, ensuring minimal cell clumping and maintaining cell integrity. Its buffering capacity and EDTA content make it a versatile tool in maintaining experimental conditions and improving the efficiency of various laboratory procedures.