tert-Butyl aziridine-1-carboxylate
≥95%
Reagent
Code: #148473
CAS Number
97308-23-1
blur_circular Chemical Specifications
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Molecular Information
Weight
143.18 g/mol
Formula
C₇H₁₃NO₂
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Registry Numbers
MDL Number
MFCD16036961
thermostat
Physical Properties
Boiling Point
174.8±9.0°C at 760 mmHg
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Storage & Handling
Storage
-20°C, dry seal
description Product Description
Used as a protected form of aziridine in organic synthesis, particularly in the preparation of nitrogen-containing compounds such as amino acids, alkaloids, and pharmaceuticals. Its tert-butoxycarbonyl (Boc) group stabilizes the aziridine ring during reactions and can be removed under mild acidic conditions, allowing controlled ring-opening and functionalization. Commonly employed in medicinal chemistry for building constrained heterocyclic scaffolds that enhance metabolic stability and bioavailability in drug candidates. Also serves as a chiral building block in asymmetric synthesis due to the ring strain of aziridine, enabling regioselective and stereoselective transformations.
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