t-Boc-Aminooxy-PEG2-azide is a bifunctional PEG linker featuring a t-Boc-protected aminooxy group, a PEG2 chain, and an azide terminus. It is used primarily in bioconjugation and click chemistry, where the aminooxy group enables oxime ligation with aldehydes or ketones on biomolecules, and the azide facilitates copper-free or catalyzed click reactions with alkynes. This compound is particularly valuable in the development of drug delivery systems, linking drugs to carriers like nanoparticles for targeted therapies. Additionally, it plays a crucial role in synthesizing bioconjugates for diagnostics, enabling precise labeling of proteins, antibodies, or other biomolecules for imaging and detection. The PEG chain enhances solubility and biocompatibility, while the t-Boc group allows for deprotection and controlled reactivity, making it essential for advanced biomedical research and therapeutic development.