Bromo-PEG6-azid is widely utilized in bioconjugation and click chemistry applications due to its functional groups. The bromo moiety allows for alkylation reactions, enabling the attachment of the molecule to thiols or other nucleophiles in proteins or peptides. The azide group is highly reactive in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, making it a key component for labeling or crosslinking biomolecules. This compound is particularly useful in drug delivery systems, where it serves as a linker to attach therapeutic agents to targeting molecules. Additionally, it is employed in the development of polymer-based materials and surface modifications, where its PEG spacer enhances solubility and reduces immunogenicity. Its versatility also extends to proteomics and bioimaging, where it facilitates the study of protein interactions and cellular processes.