This chemical is widely used in bioconjugation and chemical biology due to its reactive ester group and azide functionality. The pentafluorophenyl (PFP) ester reacts efficiently with primary amines, enabling the attachment of molecules like peptides, proteins, or other amine-containing compounds. The azide group allows for further modification via click chemistry, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), making it a valuable tool for labeling, crosslinking, or functionalizing biomolecules. Its PEG6 spacer enhances solubility and reduces steric hindrance, improving reaction efficiency in aqueous systems. This compound is particularly useful in drug delivery, surface modification, and the development of diagnostic probes or biomaterials.