1'-(tert-Butoxycarbonyl)spiro[indene-1,4'-piperidine]-3-carboxylic acid
≥95%
Reagent
Code: #148158
CAS Number
209128-15-4
blur_circular Chemical Specifications
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Molecular Information
Weight
329.39 g/mol
Formula
C₁₉H₂₃NO₄
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Registry Numbers
MDL Number
MFCD11519415
thermostat
Physical Properties
Boiling Point
475.859°C at 760 mmHg
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Storage & Handling
Density
1.253g/cm3
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its spirocyclic structure and functional groups make it valuable for constructing complex molecules with high selectivity and potency. Commonly employed in medicinal chemistry for creating modulators of neurotransmitter receptors, especially serotonin and dopamine receptor targets. The Boc-protected piperidine allows for selective deprotection and further derivatization, enabling efficient route optimization in drug discovery. Also utilized in the preparation of protease inhibitors and receptor antagonists due to its rigid framework that enhances binding affinity and metabolic stability.
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